Overall health Sciences, Winston-Salem, NC (Dr K Sink); California Healthcare Clinic for Headache, Santa Monica, CA (Dr D Kudrow); Alzheimer’s Study Corporation, Manchester, NY (Dr J Shua-Haim); University Hills Clinical Investigation, Irvine, CA (Dr MA Knisevich); Behavioral Healthcare Analysis of Staten Island, NY (Dr J Breving); Collaborative Neuroscience Network, Garden Grove, CA (Dr O Omidvar); Clinical Trials of America Inc., Winston-Salem, NC (Dr B Jones); Radiant Investigation, Denver, CO (Dr E Duboff); Clinical Study Center of Asheville LLC, Asheville, NC (Dr C Tuten); Suncoast Neuroscience Associates Inc., St. Petersburg, FL (Dr S Cohen); Bradenton Study Center, Bradenton, FL (Dr W McElveen); Lynn Wellness Science Institute, Oklahoma City, OK (Dr S Randhawa); Radiant Analysis, San Antonio, TX (Dr T Weiss); Fort Wayne Neurological Center, Fort Wayne, IN (Dr F-L Chang); University of Kentucky Health-related Center, Sanders-Brown Center on Aging, Lexington, KY (Dr G Jicha); Agewell? Indianapolis, IN (Dr S Rappaport); Premiere Study Institute, West Palm Beach, FL (Dr C Sadowsky and Dr T Villena); Healthcare University of South Carolina, Clinical Biotechnology Investigation Institute, Roper St. Francis Healthcare, and Ralph H. Johnson VA Health-related Center, North Charleston, SC (Dr J Mintzer); Radiant Analysis Inc., Chicago, IL (Dr M Kyle); Synergy Clinical Analysis Center, National City, CA (Dr M Bari); San Francisco Clinical Research Center, San Francisco, CA (Dr J Goldstein); Wake Analysis Associates LLC, Raleigh, NC (Dr A Jariwala); Beacon Clinical Investigation LLC, Brockton, MA (Dr P Sergi); Drexel University College of Medicine Department of Neurology, Philadelphia, PA (Dr C Lippa); Meridien Study, Brooksville, FL (Dr M Farmer); Meridien Research, St. Petersburg, FL (Dr G Lefebvre); Northeastern Pennsylvania Memory Alzheimer’s Center, Plains, PAConclusion This S-Connect clinical trial establishes the fact that Souvenaid as an add-on intervention will not slow general cognitive decline and is safe and effectively tolerated in persons with mild-to-moderate AD using AD medication.Fmoc-Ser-OtBu custom synthesis Additional fileAdditional file 1: Table S1. Presenting the nutritional composition of Souvenaid and control item. Abbreviations AD: Alzheimer’s illness; ADAS-cog: Alzheimer’s Disease Assessment Scale ?Cognitive Subscale; MMSE: Mini-Mental State Examination; SD: Regular deviation. Competing interests Study style and preparing have been carried out in conjunction with all the sponsor, Nutricia Analysis, on behalf of Nutricia Sophisticated Healthcare Nutrition. The sponsor also offered the study merchandise and funding for the investigation, data collection and analysis.BuyTetramethylammonium (acetate) The corresponding author had final responsibility for the selection to submit for publication.PMID:33660581 RCS serves on the Board of Directors of your Alzheimer’s Association ?Greater Illinois Chapter; serves as a member of your Investigator Consultation Network for Merck Analysis Laboratories; served on a study advisory panel for Accera, Inc., as well as a clinical advisory panel for Nutricia, Inc.; receives or recently received study help as Web-site Principal Investigator or Web page Subinvestigator from Ceregene, Inc., Eisai, Inc., Eli Lilly, Inc., Elan Pharmaceuticals, Inc., Genentech, Inc., Merck Co., Inc., Metabolic Solutions Improvement Company, Pamlab,Shah et al. Alzheimer’s Investigation Therapy 2013, five:59 http://alzres/content/5/6/Page 9 of(Dr M Cornacchione); Shepherd Healthcare, Lewisville, TX (Dr T Shepherd); Radiant Investigation, Inc., Santa Rosa, CA (Dr A B.