Product Name :
SOCS-1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
CIS1 antibody CISH 1 antibody CISH1 antibody Cytokine inducible SH2 protein 1 antibody JAB antibody JAK binding protein antibody JAK-binding protein antibody Janus kinase binding protein antibody SOCS 1 antibody SOCS-1 antibody 展开
Function :
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.127273-06-7 uses
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human SOCS-1.4-(6-Bromopyridin-3-yl)morpholine Chemical name AA range:49-98
Species reactivity:
Human, Mouse, Rat
Verify application:
IF, WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33449302 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
38 kDa
Positive control :
B-cell,Lung,Myeloid leukemia cell,T-cell lymphoma,