Product Name :
Smad4 Recombinant Rabbit Monoclonal Antibody [SP05-05]
Predicted band size :
60 kDa
Observed band size :
70 kDa
Synonyms:
(Small) Mothers Against Decapentaplegic antibody Deleted in Pancreatic Carcinoma 4 antibody Deleted in Pancreatic Carcinoma antibody Deleted in pancreatic carcinoma locus 4 antibody Deletion target in pancreatic carcinoma 4 antibody DPC 4 antibody DPC4 antibody hSMAD4 antibody JIP antibody MAD homolog 4 antibody 展开
Function :
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within C-terminal human Smad4.6-Oxa-1-azaspiro[3.3]heptane hemioxalate supplier
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC
Coupling :
unconjugated
Clone number:
SP05-05
RRID:
AB_3073456
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Formula of tert-butyl (5-bromopentyl)carbamate Aliquot store at -20℃ or -80℃.PMID:33625673 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 60 kDa
Positive control :
HeLa cell lysate, HCT 116 cell lysate, C6 cell lysate, Neuro-2a cell lysates, HeLa, Neuro-2a, PC-12, human colon tissue, human lung tissue, mouse lung tissue, rat lung tissue.